BioTech Encyclopedia

Platinum (cancer drugs and catalysis): uses in research

Also: cisplatin, platinum catalysts

Platinum compounds such as cisplatin are major cancer drugs, and platinum metal is a key catalyst in fuel cells.

Readiness: lab lab studies · prototype demonstrated objects · commercial products or buildings in real use · review summaries of other studies.

biomedical

lab biomedical 1965

Accidental discovery of platinum effects

Rosenberg and colleagues found that products from platinum electrodes stopped bacteria from dividing.

As reported in: ROSENBERG, VAN CAMP, KRIGAS (1965). Inhibition of Cell Division in Escherichia coli by Electrolysis Products from a Platinum Electrode. Nature. doi:10.1038/205698a0

Abstract only

lab biomedical 1969

Platinum anticancer compounds

Rosenberg and colleagues reported platinum compounds as potent antitumor agents, leading to cisplatin.

As reported in: ROSENBERG, VANCAMP, TROSKO et al. (1969). Platinum Compounds: a New Class of Potent Antitumour Agents. Nature. doi:10.1038/222385a0

Abstract only

energy

lab energy 2007

Platinum-nickel fuel cell catalyst

Stamenkovic and colleagues showed a Pt3Ni surface greatly improves the oxygen reaction used in fuel cells.

As reported in: Stamenkovic, Fowler, Mun et al. (2007). Improved Oxygen Reduction Activity on Pt <sub>3</sub> Ni(111) via Increased Surface Site Availability. Science. doi:10.1126/science.1135941

Abstract only