BioTech Encyclopedia

Spider silk proteins: uses in research

Also: spidroin, dragline silk, recombinant spider silk

Spider dragline silk is famous for combining strength and toughness. Spiders cannot be farmed like silkworms, so researchers produce spider silk proteins (spidroins) in microbes and spin them into artificial fibres.

Readiness: lab lab studies · prototype demonstrated objects · commercial products or buildings in real use · review summaries of other studies.

biotechnology

lab biotechnology 2010

Native-sized spider silk from E. coli

Produced native-sized recombinant spider silk protein in metabolically engineered E. coli and spun it into a strong fibre.

Built / tested: silk fibres

As reported in: Xia, Qian, Ki et al. (2010). Native-sized recombinant spider silk protein produced in metabolically engineered <i>Escherichia coli</i> results in a strong fiber. Proceedings of the National Academy of Sciences. doi:10.1073/pnas.1003366107

Read free · preprint / author manuscript

lab biotechnology 2009

Protocol for spinnable silk proteins

A protocol for producing recombinant spider silk-like proteins for artificial fibre spinning.

Built / tested: artificial fibres

As reported in: Teulé, Cooper, Furin et al. (2009). A protocol for the production of recombinant spider silk-like proteins for artificial fiber spinning. Nature Protocols. doi:10.1038/nprot.2008.250

Read free · preprint / author manuscript

genetics

lab genetics 2007

Full-length dragline silk genes

Reported full-length spider dragline silk gene sequences as a blueprint for a high-performance biomaterial.

As reported in: Ayoub, Garb, Tinghitella et al. (2007). Blueprint for a High-Performance Biomaterial: Full-Length Spider Dragline Silk Genes. PLoS ONE. doi:10.1371/journal.pone.0000514

Read free · publisher open access

materials science

review materials science 1999

Sequence, structure and strength

Hypotheses linking the sequence, structure and mechanical properties of spider silk proteins.

As reported in: Hayashi, Shipley, Lewis (1999). Hypotheses that correlate the sequence, structure, and mechanical properties of spider silk proteins. International Journal of Biological Macromolecules. doi:10.1016/s0141-8130(98)00089-0

Abstract only

lab materials science 2015

Fibres as tough as natural silk

Biomimetic fibres made of recombinant spidroins with the same toughness as natural spider silk.

Built / tested: biomimetic fibres

As reported in: Heidebrecht, Eisoldt, Diehl et al. (2015). Biomimetic Fibers Made of Recombinant Spidroins with the Same Toughness as Natural Spider Silk. Advanced Materials. doi:10.1002/adma.201404234

Abstract only