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Kragl and colleagues tracked GFP-labelled cells and found each limb tissue makes progenitors with restricted potential, so limbs regrow without cells becoming fully pluripotent.
As reported in: Kragl, Knapp, Nacu et al. (2009). Cells keep a memory of their tissue origin during axolotl limb regeneration. Nature. doi:10.1038/nature08152
Nowoshilow and colleagues assembled the 32-gigabase axolotl genome and found evidence that species-restricted genes may contribute to limb regeneration.
As reported in: Nowoshilow, Schloissnig, Fei et al. (2018). The axolotl genome and the evolution of key tissue formation regulators. Nature. doi:10.1038/nature25458