BioTech Encyclopedia

Coral (coralline bone substitutes): uses in research

Also: coralline hydroxyapatite, calcium carbonate coral, Porites

Coral skeletons have a porous structure much like bone. Natural coral and coral converted to hydroxyapatite have been used as bone graft substitutes and implants.

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Timeline

  1. 1979 Coralline hydroxyapatite implant
  2. 1987 Coral as a bone graft substitute
  3. 2007 Stem cells on coral scaffolds

Readiness: lab lab studies · prototype demonstrated objects · commercial products or buildings in real use · review summaries of other studies.
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biomedical

commercial biomedical 1979

Coralline hydroxyapatite implant

Holmes reported bone regrowing in dogs within coral-derived hydroxyapatite implants.

Built / tested: coralline hydroxyapatite

As reported in: Holmes (1979). Bone Regeneration Within a Coralline Hydroxyapatite Implant. Plastic and Reconstructive Surgery. doi:10.1097/00006534-197905000-00004

Abstract only

lab biomedical 1987

Coral as a bone graft substitute

Guillemin and colleagues studied natural coral as a bone graft substitute.

As reported in: Guillemin, Patat, Fournie et al. (1987). The use of coral as a bone graft substitute. Journal of Biomedical Materials Research. doi:10.1002/jbm.820210503

Abstract only

biomedical research

lab biomedical research 2007

Stem cells on coral scaffolds

Mygind and colleagues grew mesenchymal stem cells on coralline hydroxyapatite scaffolds.

As reported in: Mygind, Stiehler, Baatrup et al. (2007). Mesenchymal stem cell ingrowth and differentiation on coralline hydroxyapatite scaffolds. Biomaterials. doi:10.1016/j.biomaterials.2006.10.003

Abstract only