BioTech Encyclopedia

Embryonic stem cells: uses in research

Also: ES cells, hESC, pluripotent stem cells

Embryonic stem cells come from very early embryos and can grow indefinitely and become any body cell type. They opened modern stem cell biology.

Patents

Search Google Patents for this topic: all patents · recent applications (2022+)

Patent searches are generated from the topic's key terms; a patent is a legal claim, not proof that something works. See the Patents page.

Timeline

  1. 1981 Mouse ES cells (Evans and Kaufman)Mouse ES cells (Martin)
  2. 1998 First human ES cell lines

Readiness: lab lab studies · prototype demonstrated objects · commercial products or buildings in real use · review summaries of other studies.
Export this topic's references: BibTeX · RIS (Zotero, EndNote, Mendeley)

Filter:

biomedical research

lab biomedical research 1981

Mouse ES cells (Evans and Kaufman)

Evans and Kaufman established pluripotent cell lines grown from mouse embryos.

Built / tested: mouse ES cell lines

As reported in: Evans, Kaufman (1981). Establishment in culture of pluripotential cells from mouse embryos. Nature. doi:10.1038/292154a0

Abstract only

lab biomedical research 1981

Mouse ES cells (Martin)

Gail Martin independently isolated a pluripotent cell line from early mouse embryos and coined the term embryonic stem cell.

Built / tested: mouse ES cell lines

As reported in: Martin (1981). Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells.. Proceedings of the National Academy of Sciences. doi:10.1073/pnas.78.12.7634

Read free · preprint / author manuscript

lab biomedical research 1998

First human ES cell lines

Thomson and colleagues derived the first human embryonic stem cell lines from blastocysts.

Built / tested: human ES cell lines

As reported in: Thomson, Itskovitz-Eldor, Shapiro et al. (1998). Embryonic Stem Cell Lines Derived from Human Blastocysts. Science. doi:10.1126/science.282.5391.1145

Abstract only