Also: JCVI-syn1.0, JCVI-syn3.0, minimal cell
Scientists at the J. Craig Venter Institute built bacteria run by fully chemically made genomes, then trimmed them to a minimal set of genes.
Readiness: lab lab studies · prototype demonstrated objects · commercial products or buildings in real use · review summaries of other studies.
Gibson and colleagues created a bacterial cell controlled by a chemically synthesized genome (JCVI-syn1.0).
As reported in: Gibson, Glass, Lartigue et al. (2010). Creation of a Bacterial Cell Controlled by a Chemically Synthesized Genome. Science. doi:10.1126/science.1190719
Hutchison and colleagues designed and built a minimal bacterial genome (JCVI-syn3.0).
As reported in: Hutchison, Chuang, Noskov et al. (2016). Design and synthesis of a minimal bacterial genome. Science. doi:10.1126/science.aad6253
Abstract only
Pelletier and colleagues found which genes the minimal cell needs to divide normally.
As reported in: Pelletier, Sun, Wise et al. (2021). Genetic requirements for cell division in a genomically minimal cell. Cell. doi:10.1016/j.cell.2021.03.008