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Kriegman and colleagues used AI to design new lifeforms in simulation and built them from frog cells, which then showed the predicted behaviours.
As reported in: Kriegman, Blackiston, Levin et al. (2020). A scalable pipeline for designing reconfigurable organisms. Proceedings of the National Academy of Sciences. doi:10.1073/pnas.1910837117
Kriegman and colleagues found clusters of frog cells could gather loose cells into new working copies, a form of self-replication not seen in any organism.
As reported in: Kriegman, Blackiston, Levin et al. (2021). Kinematic self-replication in reconfigurable organisms. Proceedings of the National Academy of Sciences. doi:10.1073/pnas.2112672118