BioTech Encyclopedia

Deinococcus radiodurans

Experiments: basic research on living systems, not technology.

Also: Conan the bacterium

A bacterium that survives radiation doses that shatter its genome, then puts its DNA back together.

Known properties: Deinococcus radiodurans

Only what the cited papers report.

Key measured values

Values as stated in the cited paper's abstract.

PropertyValueSource
Growth under chronic gamma radiation50 Gy per hourDaly 2004
Recovery from acute dose>10 kGyDaly 2004
Genome size3.28 megabasesZahradka 2006

Uses proposed by researchers for this topic are listed on Potential uses.

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Timeline

  1. 2000 Engineered to clean radioactive waste
  2. 2004 Manganese protects it
  3. 2006 Reassembling a shattered genome

Readiness: lab lab studies · prototype demonstrated objects · commercial products or buildings in real use · review summaries of other studies.
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lab biology 2004

Manganese protects it

Daly and colleagues found D. radiodurans accumulates very high manganese and low iron, and proposed that Mn(II) helps it recover from radiation injury.

As reported in: Daly, Gaidamakova, Matrosova et al. (2004). Accumulation of Mn(II) in <i>Deinococcus radiodurans</i> Facilitates Gamma-Radiation Resistance. Science. doi:10.1126/science.1103185

Abstract only

lab biology 2006

Reassembling a shattered genome

Zahradka and colleagues described how D. radiodurans reassembles hundreds of genome fragments using a process they called ESDSA, followed by crossovers.

As reported in: Zahradka, Slade, Bailone et al. (2006). Reassembly of shattered chromosomes in Deinococcus radiodurans. Nature. doi:10.1038/nature05160

Abstract only

prototype biology 2000

Engineered to clean radioactive waste

Brim and colleagues engineered D. radiodurans to treat mixed radioactive waste containing ionic mercury.

As reported in: Brim, McFarlan, Fredrickson et al. (2000). Engineering Deinococcus radiodurans for metal remediation in radioactive mixed waste environments. Nature Biotechnology. doi:10.1038/71986

Abstract only

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